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Symbol
Name
ID

Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
MGI:1206581

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Meningioma	Spinal dysraphism	Tethered cord	Intention tremor	Intellectual disability	Intellectual disability, mild	Seizure
Disease(s) Associated with PIK3CA	Meningioma	Spinal dysraphism	Tethered cord	Intention tremor	Intellectual disability	Intellectual disability, mild	Seizure
CLOVES syndrome
Cowden syndrome 5

Mouse Phenotypes		abnormal brain vasculature morphology	retina cone cell degeneration	abnormal myelination
Availability	Mouse Genotype	abnormal brain vasculature morphology	retina cone cell degeneration	abnormal myelination
	Pik3ca^tm1Nbm/Pik3ca^tm1Nbm
	Pik3ca^tm1Jjz/Pik3ca^tm1Jjz Tg(OPN1LW-cre)4Yzl/0 (conditional)
	Egr2^tm2(cre)Pch/Egr2⁺ Gt(ROSA)26Sor^{tm7(Pik3ca*,EGFP)Rsky}/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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